Teeth that don't regenerate may be a thing of the past, but scientists are bringing them back to life.

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In the marvellous journey of life, most people will have a period with two sets of teeth, as if they were given two chances to smile by nature. At first, when the clock strikes the six-month mark, tiny baby teeth poke their way through the gums of babies. Once the age of six has passed, it's as if the baby teeth have completed their mission and begin to retire one by one, making way for stronger, longer-lasting permanent teeth. However, not everyone's dental story is written so smoothly. Some people, at some point in their lives, suffer the misfortune of missing teeth, and the smile that is dimmed by their absence becomes a hidden pain in their hearts.

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Fortunately, the highly skilled oral guardians have finally developed a miraculous drug - it can awaken the regenerative power of sleeping in the depths of life, so that mice and ferrets, these small animals miraculously regrow their missing teeth. This breakthrough discovery is like a warm ray of sunshine that penetrates the haze that has long hung over the hearts of people with missing teeth. The innovative treatment is about to take a historic step forward - from September it will be tested on humans for the first time.

If the process of tooth growth is a car race, then USAG-1 is the referee who presses the pause button at the critical moment, mercilessly blocking the eruption of new teeth and leaving many people's smiles incomplete and regrettable. But wise dental scientists, like a group of courageous race car engineers, have discovered this hidden ‘braking mechanism’ and developed a miracle drug specifically designed to ‘unlock’ it and get the tooth growth engine roaring again. The drug acts as a precision key, subtly inhibiting the activity of USAG-1 and clearing the way for teeth to grow. Even more surprisingly, the drug not only helped spawn brand new teeth at the vacancies, it also strengthened the bone structure of the existing teeth like reinforcing the masonry of a castle, making each tooth stronger and more durable, as if putting an invisible layer of armour on the smile. In ferrets and rats, which share similar USAG-1 characteristics with humans, the drug performed perfectly. Instead of any uncomfortable ‘side effect alerts’, they showed the miraculous growth of new teeth healthily and energetically.

If this miraculous journey of teeth reaches the other side, the researchers have a warm and ambitious vision in mind. They want to give this precious ‘gift of tooth regeneration’ to little angels between the ages of 2 and 7 who are born with incomplete smiles - children who have been missing at least four of their precious teeth since birth due to congenital dental defects. And that is just the beginning.

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The researchers have even bigger dreams in mind. They hope that as their research progresses and the technology matures, they will be able to extend the benefits of tooth regeneration to more people who have lost their permanent teeth due to environmental factors - whether it's teeth lost in an accidental fall, or teeth that have gradually fallen out over the years. Precious smiles. Whether it's one, two, or as many as five missing teeth, they are going all out with the power of science. This is a journey of love and hope, and every step of the way unites the wisdom and sweat of the researchers. They believe that one day in the future when every smile can bloom freely under the sun, this miracle about tooth regeneration will become a bridge connecting hearts and warming the world.

Shortly, those who have lost their confident smiles due to missing teeth may be able to usher in their moment of rebirth, blossoming a bright and confident smile again, making the flower of life more gorgeous and eye-catching in every smile. Whether it is due to mischievousness at a young age, accidentally knocking out a tooth, or having to painfully say goodbye to a beloved tooth due to tooth decay, it will no longer be a regret that is hard to let go of in your heart.

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